Download PDF by Shinji Funayama, Geoffrey A. Cordell: Alkaloids: A Treasury of Poisons and Medicines

By Shinji Funayama, Geoffrey A. Cordell

ISBN-10: 0124173020

ISBN-13: 9780124173026

Alkaloids are a wide workforce of structurally complicated usual items showing quite a lot of organic actions. the aim of Alkaloids: A Treasury of toxins and drugs is to categorise, for the 1st time, the alkaloids remoted from the ordinary assets beforehand. The publication classifies the entire alkaloids via their biosynthetic origins. Of curiosity to the natural chemistry and medicinal chemistry groups interested by drug discovery and improvement, this e-book describes many alkaloids remoted from the medicinal vegetation, together with these utilized in eastern Kampo medicine.

  • Classifies and lists alkaloids from traditional sources
  • Occurrence and biosynthetic pathways of alkaloids
  • Indicates key makes use of and bioactivity of alkaloids

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Extra info for Alkaloids: A Treasury of Poisons and Medicines

Example text

Kaneda, J. Chem. Soc. (C) 2036 (1969). [4] H. Fujimura, T. Sawada, M. Goto,Yakugaku Zasshi 90 (1970) 782. [5] Y. Kondo, H. Suzuki, Shoyakugaku Zasshi 45 (1991) 35. [6] S. Funayama, N. Haga, K. Kurumada, S. Nozoe, M. Hayashi, K. Komiyama, Nat. Med. 50 (1996) 427. [7] P. Steffens, N. H. Zenk, Phytochemistry 24 (1985) 2577. [8] S. Muemmler, M. Rueffer, N. H. Zenk, Plant Cell Rep. 3 (1985) 26. [9] M. Amann, N. H. Zenk, Tetrahedron Lett. 25 (1984) 953. [10] M. H. Zenk, Tetrahedron Lett. 26 (1985) 201.

C. R. Battersby, E. McDonald, R. H. Clements, Chem. Commun. 390 (1967). R. B. Herbert, L. Pijewska, F. Santavy, P. Sedmera, J. Chem. Soc. Perkin Trans. 1736 (1972). R. B. Herbert, E. McDonald, R. H. Clements, J. Chem. Soc. Perkin Trans. 1741 (1972). R. W. A. Milner, Tetrahedron Lett. 15 (1974) 3315. D. M. Unrau, Can. J. Chem. 43 (1965) 709. [11] O. Boye, A. Brossi, Alkaloids 41 (1992) 125. 12  Erythrina indica AND ERYTHRINA ALKALOIDS Erythrina indica (=E. variegata var. orientalis) (Fabaceae) is a deciduous tree, and is the symbolic flower of Okinawa prefecture in Japan.

Soc. Perkin Trans. I 346 (1974). S. N. Singh, J. Chem. Soc. Perkin Trans. I 618 (1978). [9] K. Ito, H. Furukawa, H. Tanaka, Chem. Pharm. Bull. 19 (1971) 1509. 13  Lycoris spp. AND LYCORINE Some Amaryllidaceae plants possess a group of alkaloids containing a C6– C2–N–C1–C6 unit. In this unit, the C6–C2–N moiety is derived from tyrosine or tyramine, and the C6–C1 part is derived from phenylalanine through cinnamic acid, p-coumaric acid, and protocatechualdehyde [1]. Tyramine (C6–C2–N unit) and protocatechualdehyde (C6–C1 unit) are then combined and methylated to form O-methylnorbelladine, which is a common biosynthetic precursor of various Amaryllidaceae alkaloids.

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Alkaloids: A Treasury of Poisons and Medicines by Shinji Funayama, Geoffrey A. Cordell


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